8th January 2010

                             REGEN THERAPEUTICS PLC
                   (“ReGen” or the “Company”; Ticker: (RGT))


               TR-1(i): NOTIFICATION OF MAJOR INTEREST IN SHARES



 1. Identity of the issuer or the           ReGen Therapeutics Plc
 underlying issuer of existing shares to
 which voting rights are attached (ii):


 2. Reason for the notification:            An acquisition or disposal of
                                            voting rights


 3. Full name of person(s) subject to the   Andrew Clement Wilson
 notification obligation (iii):


 4. Full name of shareholder(s) (if         As Above
 difference from 3):


 5. Date of the transaction and date on     7th January 2010
 which the threshold is crossed or reached
 (v):


 6. Date on which issuer notified:          8th January 2010


 7. Threshold(s) that is/are crossed or     5%
 reached:


 8. Notified details


 A: Voting rights attached to shares


 Class/type of share if possible using the  GB00B28XMY25
 ISIN Code



 Situation Previous to the triggering
 transaction (vi) –

 Number of Shares                           2,590,000

 Number of Voting Rights (viii)             2,590,000



 Resulting situation after the triggering
 transaction (viii) –

 Number of Shares                           1,527,000

 Number of Voting Rights – Direct (x)       1,527,000

 Number of Voting Rights – Indirect (xi)    N/A

 % of voting rights – Direct                4.157%

 % of voting rights – Indirect              N/A



 B: Financial Instruments


 Resulting situation after the triggering
 transaction (xii)



 Type of financial instrument               N/A

 Expiration date (xiii)                     N/A

 Exercise/Conversion Period/Date (xiv)      N/A

 Number of voting rights that may be        N/A
 acquired if the instrument is
 exercised/converted

 % of voting rights                         N/A



 C: Financial Instruments with similar economic effect to Qualifying Financial
 Instruments



 Resulting situation after the triggering
 transaction



 Type of financial instrument               N/A

 Exercise Price                             N/A

 Expiration Date                            N/A

 Exercise Conversion Period                 N/A

 Number of voting rights                    N/A
 Instrument refers to

 % of voting rights                         N/A



 Total (A+B+C)


 Number of voting rights                    1,527,000

 % of voting rights                         4.157





 9. Chain of controlled undertakings
 through which the voting rights and/or the
 financial instruments are effectively
 held, if applicable (xv):



 Proxy Voting:


 10. Name of the proxy holder:              Wapole St Andrews Nominee

 11. Number of voting rights proxy holder   N/A
 will cease to hold:

 12. Date on which proxy holder will cease  N/A
 to hold voting rights:

 13. Additional information:                N/A

 14. Contact name:                          Patrick Wilson

 15. Contact telephone number:              028 90 434040









For further information:

For further information, please contact:

Percy Lomax
ReGen Therapeutics Plc
Tel: 020 7153 4920

Roland Cornish/Felicity Geidt
Beaumont Cornish Limited
Tel: 020 7628 3396

David Scott /Nick Bealer
Alexander David Securities Limited
Tel: 020 7448 9800


[HUG#1371846]