TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Vectura Group plc  

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

X 

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

3. Full name of person(s) subject to the notification obligation:

Aviva plc & its subsidiaries 

4. Full name of shareholder(s) (if different from 3.):

Registered Holder:

BNY Norwich Union Nominees
Limited                                      2,094,981*

Chase (GA Group) Nominees  
Limited                                    13,737,590*

Chase Nominees Limited            164,683*

CUIM Nominee Limited            1,091,409*

*denotes direct interest

BNP Paribas - London                 536,024

Chase Nominees Limited          5,552,776

State Street Nominees Limited  6,800,080

Vidacos Nominees Limited        2,513,695

5. Date of the transaction and date on which the threshold is crossed or reached:

07 January 2010 

6. Date on which issuer notified:

08 January 2010 

7. Threshold(s) that is/are crossed or reached:

<10% to 10% Change at Combined Interest Level 

8. Notified details:

A: Voting rights attached to shares

Class/type of
shares

if possible using
the ISIN CODE

Situation previous
to the triggering
transaction

Resulting situation after the triggering transaction

Number
of
Shares

Number
of
Voting
Rights

Number
of shares

Number of voting
rights

% of voting rights

Direct

Direct

Indirect

Direct

Indirect

Ordinary Shares 

32,247,166 

32,247,166 

32,491,238 

17,088,663 

15,402,575 

5.28% 

4.76% 

B00B01D1K48 

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial
instrument

Expiration
date

Exercise/ 
Conversion 
Period

Number of voting
rights that may be
acquired if the
instrument is
exercised/ converted.

% of voting
rights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial
instrument

Exercise 
price

Expiration 
date

Exercise/
Conversion 
period

Number of voting 
rights instrument 
refers to

% of voting rights

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

32,491,238 

10.04% 

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:

The voting rights are managed and controlled by Aviva Investors Global Services Limited, with the following chain of controlled undertakings:-

Aviva Investors Global Services Limited: 
- Aviva plc (Parent Company)
- Aviva Group Holdings Limited (wholly owned subsidiary of Aviva plc)
- Aviva Investors Holdings Limited (wholly owned subsidiary of Aviva Group Holdings Limited)
- Aviva Investors Global Services Limited (wholly owned subsidiary of Aviva Investors Holdings Limited)

Proxy Voting:

10. Name of the proxy holder:

See Section 4 

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

Figures are based on a total number of voting rights of 323,376,489. 

14. Contact name:

Neil Whittaker 

15. Contact telephone number:

01603 684420