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Wednesday 23 December, 2009

Antisoma plc

Holding(s) in Company







                            Holdings in Antisoma plc


+------------------------------------------------------------------------------+
|TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES                                |
+------------------------------------------------------------------------------+

+----------------------------------------------+-------------------------------+
|1. Identity of the issuer or the underlying   |                               |
|issuer                                        |                               |
|of existing shares to which voting rights are |         Antisoma Plc          |
|attached:                                     |                               |
|                                              |                               |
+----------------------------------------------+-------------------------------+
|2. Reason for the notification(please tick the appropriate box or boxes):     |
+--------------------------------------------------------------------+---------+
|An acquisition or disposal of voting rights                         |   Yes   |
+--------------------------------------------------------------------+---------+
|                                                                    |         |
|An acquisition or disposal of qualifying financial instruments which|         |
|may result in the acquisition of shares already issued to which     |         |
|voting rights are attached.                                         |         |
|                                                                    |         |
+--------------------------------------------------------------------+---------+
|                                                                    |         |
|An acquisition or disposal of instruments with similar economic     |         |
|effect to qualifying financial instruments                          |         |
|                                                                    |         |
+--------------------------------------------------------------------+---------+
|An event changing the breakdown of voting rights                    |         |
+--------------------------------------------------------------------+---------+
|                                                                    |         |
|Other (please specify):                                             |         |
|                                                                    |         |
+--------------------------------------+-----------------------------+---------+
|3. Full name of person(s) subject to  |                                       |
|the                                   |    Legal & General Group Plc (L&G)    |
|notification obligation:              |                                       |
+--------------------------------------+---------------------------------------+
|4. Full name of shareholder(s)        |  Legal & General Assurance (Pensions  |
|(if different from 3.):               |       Management) Limited (PMC)       |
+--------------------------------------+---------------------------------------+
|                                      |                                       |
|5. Date of the transaction and date on|                                       |
|which the threshold is crossed or     |           21 December 2009            |
|reached:                              |                                       |
|                                      |                                       |
+--------------------------------------+---------------------------------------+
|6. Date on which issuer notified:     |           22 December 2009            |
+--------------------------------------+---------------------------------------+
|7. Threshold(s) that is/are crossed or|                                       |
|reached:                              |          L&G (From 4% to 3%)          |
|                                      |                                       |
+--------------------------------------+---------------------------------------+

+------------------------------------------------------------------------------+
|8. Notified details:                                                          |
|                                                                              |
+------------------------------------------------------------------------------+
|A: Voting rights attached to shares                                           |
+-----------+--------------+---------------------------------------------------+
|Class/type |  Situation   |     Resulting situation after the triggering      |
|of         |   previous   |                    transaction                    |
|shares     |    to the    |                                                   |
|           |  triggering  |                                                   |
|if possible| transaction  |                                                   |
|using      +------+-------+------------+---------------------+----------------+
|the ISIN   |Number|Number |            |  Number of voting   |  % of  voting  |
|CODE       |  of  |  of   |   Number   |       rights        |     rights     |
|           |  ares|Vot ng | of sha  s  +------------+--------+-------+--------+
|           |      |Rights |            |   Direct   |Indirect|Direct |Indirect|
+-----------+------+-------+------------+------------+--------+-------+--------+
|           |  24,954,039  |            |            |        |       |        |
|Ordinary 1p|              | 24,579,841 | 24,579,841 |        | 3.93% |        |
|           |     (As      |            |            |        |       |        |
|           |on16/06/2009) |            |            |        |       |        |
+-----------+--------------+------------+------------+--------+-------+--------+

+------------------------------------------------------------------------------+
|B: Qualifying Financial Instruments                                           |
+------------------------------------------------------------------------------+
|Resulting situation after the triggering transaction                          |
+-------------+-----------+---------------------+----------------+-------------+
|             |           |                     |Number of voting|             |
|Type of      |Expiration |Exercise/            |rights that may |% of voting  |
|financial    |date       |Conversion Period    |be              |rights       |
|instrument   |           |                     |acquired if the |             |
|             |           |                     |instrument is   |             |
|             |           |                     |exercised/      |             |
|             |           |                     |converted.      |             |
+-------------+-----------+---------------------+----------------+-------------+
|             |           |                     |                |             |
+-------------+-----------+---------------------+----------------+-------------+

+------------------------------------------------------------------------------+
|C: Financial Instruments with similar economic effect to Qualifying Financial |
|Instruments                                                                   |
+------------------------------------------------------------------------------+
|Resulting situation after the triggering transaction                          |
+------------+---------+-----------+-----------+----------------+--------------+
|            |         |           |           |                |              |
|Type      of|Exercise |Expiration |Exercise/  |Number of voting|%   of  voting|
|financial   |price    |date       |Conversion |rights          |rights        |
|instrument  |         |           |period     |instrument      |              |
|            |         |           |           |refers to       |              |
|            |         |           |           |                |              |
+------------+---------+-----------+-----------+----------------+-------+------+
|            |         |           |           |                |Nominal|Delta |
|            |         |           |           |                +-------+------+
|            |         |           |           |                |       |      |
+------------+---------+-----------+-----------+----------------+-------+------+

+------------------------------------------------------------------------------+
|Total (A+B+C)                                                                 |
+-----------------------------------+------------------------------------------+
|Number of voting rights            |Percentage of voting rights               |
+-----------------------------------+------------------------------------------+
|                                   |                                          |
|             24,579,841            |                  3.93%                   |
|                                   |                                          |
+-----------------------------------+------------------------------------------+

+------------------------------------------------------------------------------+
|9. Chain of controlled undertakings through which the voting rights and/or the|
|financial instruments are effectively held, if applicable:                    |
+------------------------------------------------------------------------------+
|                                                                              |
| Legal & General Group Plc (Direct and                                        |
| Indirect) (Group)                                                            |
|                                                                              |
| Legal & General Investment Management                                        |
| (Holdings) Limited (LGIMH) (Direct and                                       |
| Indirect)                                                                    |
|                                                                              |
| Legal & General Investment Management                                        |
| Limited (Indirect) (LGIM)                                                    |
|                                                                              |
| Legal & General Group Plc (Direct) (L&G) ( 24,579,841 – 3.93%= LGAS, LGPL &  |
|                                     PMC)                                     |
|                                                                              |
| Legal & General Investment Management   Legal & General Insurance Holdings   |
| (Holdings) Limited (Direct) (LGIMHD) (  Limited (Direct) (LGIH)              |
| 21,029,421 – 3.36%= PMC)                                                     |
|                                                                              |
| Legal & General Assurance (Pensions     Legal & General Assurance Society    |
| Management) Limited  (PMC) (            Limited  (LGAS & LGPL)               |
| 21,029,421 – 3.36%= PMC)                                                     |
|                                                                              |
|                                         Legal & General Pensions Limited     |
|                                         (Direct)  (LGPL)                     |
|                                                                              |
+------------------------------------------------------------------------------+

+------------------------------------------------------------------------------+
|Proxy Voting:                                                                 |
+-----------------------------------------------+------------------------------+
|10. Name of the proxy holder:                  |             N/A              |
+-----------------------------------------------+------------------------------+
|11. Number of voting rights proxy holder will  |             N/A              |
|cease                                          |                              |
|to hold:                                       |                              |
+-----------------------------------------------+------------------------------+
|12. Date on which proxy holder will cease to   |             N/A              |
|hold                                           |                              |
|voting rights:                                 |                              |
+-----------------------------------------------+------------------------------+

+-----------------------------+------------------------------------------------+
|                             |   Notification using the total voting rights   |
|13. Additional information:  |             figure of 625,285,385              |
|                             |                                                |
|                             |                                                |
+-----------------------------+------------------------------------------------+
|14. Contact name:            |               Helen Lewis (LGIM)               |
+-----------------------------+------------------------------------------------+
|15. Contact telephone number:|                 020 3124 3851                  |
+-----------------------------+------------------------------------------------+



Enquiries:
Alison Saville, Senior Marketing and Communications Executive
Antisoma plc
+44 (0)20 3249 2144



[HUG#1367347]







	




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