Antisoma plc

                      Director's Share Dealing

18 November 2009, London, UK,  and Cambridge, MA: Antisoma plc  (LSE:
ASM; USOTC:  ATSMY) announces  that its  Chairman, Barry  Price,  has
purchased 1p ordinary Antisoma shares as follows:


+------------------------------------------------------------------------+
|Director  |Date of      |Amount     |Price  |Total amount |% of Company |
|          |transaction  |of shares  |(p)    |of           |held         |
|          |             |purchased  |       |shares held  |following the|
|          |             |           |       |in the       |transaction  |
|          |             |           |       |Company      |             |
|          |             |           |       |following    |             |
|          |             |           |       |the          |             |
|          |             |           |       |transaction  |             |
|----------+-------------+-----------+-------+-------------+-------------|
|Barry     |18.11.2009   |50,000     |30.5   |793,077      |0.13%        |
|Price     |             |           |       |             |             |
+------------------------------------------------------------------------+



Enquiries:

Daniel Elger
VP, Marketing and Communications
Antisoma plc
+44 (0) 20 3249 2100

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