22nd September 2009

                       REGEN THERAPEUTICS PLC
              ("ReGen" or the "Company"; Ticker: (RGT))


TR-1(i): NOTIFICATION OF MAJOR INTEREST IN SHARES



1. Identity of the issuer or the underlying issuer of existing
shares to which voting rights are attached (ii): ReGen Therapeutics
Plc



2. Reason for the notification: An acquisition or disposal of
voting rights




3. Full name of person(s) subject to the notification obligation
(iii):
Barclays PLC




4. Full name of shareholder(s) (if difference from 3): Barclays
Stockbrokers Ltd




5. Date of the transaction and date on which the threshold is
crossed or reached (v): 18th September 2009


6. Date on which issuer notified: 22nd September 2009


7.  Threshold(s) that is/are crossed or reached: 12% to 13%


8.  Notified details

A: Voting rights attached to shares

Class/type of share if possible using the ISIN Code GB00B28XMY25

Situation Previous to the triggering transaction (vi) -
Number of Shares 4,424,730
Number of Voting Rights (viii) 4,424,730

Resulting situation after the triggering transaction (viii) -
Number of Shares 4,448,743
Number of Voting Rights - Direct (x) 0
Number of Voting Rights - Indirect (xi) 4,448,743
% of voting rights - Direct 0.00
% of voting rights - Indirect  13.00

B: Financial Instruments

Resulting situation after the triggering transaction (xii)

Type of financial instrument   n/a
Expiration date (xiii)  n/a
Exercise/Conversion Period/Date (xiv) n/a
Number of voting rights that may be acquired if the instrument is
exercised/converted
% of voting rights  n/a

C: Financial Instruments with similar economic effect to Qualifying
Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument  N/A
Exercise Price  N/A
Experation Date  N/A
Number of voting rights   N/A
Instrument refers to
% of voting rights  N/A

Total (A+B+C)


Number of voting rights  4,448,743
% of voting rights  13.00


9.  Chain of controlled undertakings through which the voting
rights and/or the financial instruments are effectively held, if
applicable (xv): Barclays Stockbrokers Ltd


Proxy Voting:

10. Name of the proxy holder:  N/A
11. Number of voting rights proxy holder will cease to hold:  N/A
12. Date on which proxy holder will cease to hold voting rights:
 N/A
13. Additional information:  N/A
14. Contact name:  Geoff Smith
15. Contact telephone number:  0207 116 2913






For further information:

For further information, please contact:
Percy Lomax
ReGen Therapeutics Plc
Tel: 020 7153 4920

Roland Cornish/Felicity Geidt
Beaumont Cornish Limited
Tel: 020 7628 3396

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