11th September 2009

                       REGEN THERAPEUTICS PLC
              ("ReGen" or the "Company"; Ticker: (RGT))


TR-1(i): NOTIFICATION OF MAJOR INTEREST IN SHARES



1. Identity of the issuer or the           ReGen Therapeutics Plc
underlying issuer of existing shares to
which voting rights are attached (ii):


2. Reason for the notification:            An event changing the
                                           breakdown of voting rights
                                           and an acquisition or
                                           disposal of voting rights


3. Full name of person(s) subject to the   Barclays PLC
notification obligation (iii):


4. Full name of shareholder(s) (if         Barclays Stockbrokers Ltd
difference from 3):


5. Date of the transaction and date on     8th  September 2009
which the threshold is crossed or reached
(v):


6. Date on which issuer notified:          10th September 2009


7.  Threshold(s) that is/are crossed or     14% to 12%
reached:

8.  Notified details

A: Voting rights attached to shares

Class/type of share if possible using the  GB00B28XMY25
ISIN Code

Situation Previous to the triggering
transaction (vi) -
Number of Shares                           4,386,487
Number of Voting Rights (viii)             4,386,487

Resulting situation after the triggering
transaction (viii) -
Number of Shares                           4,312,453
Number of Voting Rights - Direct (x)       N/A
Number of Voting Rights - Indirect (xi)    4,312,453
% of voting rights - Direct                N/A
% of voting rights - Indirect              12.60

B: Financial Instruments

Resulting situation after the triggering
transaction (xii)

Type of financial instrument               N/A
Expiration date (xiii)                     N/A
Exercise/Conversion Period/Date (xiv)      N/A
Number of voting rights that may be        N/A
acquired if the instrument is
exercised/converted
% of voting rights                         N/A

C: Financial Instruments with similar economic effect to Qualifying
Financial Instruments

Resulting situation after the triggering
transaction

Type of financial instrument               N/A
Exercise Price                             N/A
Experation Date                            N/A
Number of voting rights                    N/A
Instrument refers to
% of voting rights                         N/A

Total (A+B+C)


Number of voting rights                    4,312,453
% of voting rights                         12.60


9.  Chain of controlled undertakings       Barclays Stockbrokers Ltd
through which the voting rights and/or the
financial instruments are effectively
held, if applicable (xv):

Proxy Voting:

10. Name of the proxy holder:              N/A
11. Number of voting rights proxy holder   N/A
will cease to hold:
12. Date on which proxy holder will cease  N/A
to hold voting rights:
13. Additional information:                N/A
14. Contact name:                          Geoff Smith
15. Contact telephone number:              0207 116 2913






For further information:

For further information, please contact:
Percy Lomax
ReGen Therapeutics Plc
Tel: 020 7153 4920

Roland Cornish/Felicity Geidt
Beaumont Cornish Limited
Tel: 020 7628 3396

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